Вот в этой статье доктор индус не побоялся описать опасности аденовирусных векторов,
в частности для ЦНС и аутоимунные реакции

So can the presence of adenoviruses as a vector increase the risk of autoimmunity? We need to study this association in detail, since the human experience with these vectors, including the chimpanzee adenovirus, is paltry

https://science.thewire.in/health/covishield-what-we-need-to-know-to-understand-the-safety-of-viral-vector-vaccines/